Wednesday, March 19, 2025

MENOSCAN: HEALTH RISKS & DIAGNOSTIC MEASURES

 

Excerpt from MENOSCAN.org:
Menopause marks a significant transition in a woman’s life, bringing hormonal shifts that can increase the risk of several health conditions. As estrogen levels decline, various physiological changes take place, making postmenopausal women more susceptible to cardiovascular disease, osteoporosis, metabolic disorders, and cognitive decline. Understanding these risks and undergoing appropriate screenings can help in early intervention and preventive care.

1. CARDIOVASCULAR DISEASE (CVD):
One of the most concerning risks associated with menopause is heart disease. Estrogen plays a protective role in maintaining healthy blood vessels and cholesterol levels. Its decline leads to increased LDL (bad cholesterol), reduced HDL (good cholesterol), higher blood pressure, and arterial stiffness, all of which contribute to cardiovascular disease.


IMAGING HEART HEALTH
Ultrasound plays a vital role in assessing heart health in premenopausal women by providing a non-invasive, real-time evaluation of cardiac function. Echocardiography offers detailed imaging of the heart’s chambers, valves, and function, aiding in early detection of cardiovascular disease. As estrogen declines during menopause, risks like hypertension, arrhythmias, and reduced arterial elasticity increase. Early ultrasound detection helps guide lifestyle changes and medical interventions to prevent complications.

Carotid ultrasound is also crucial for detecting early atherosclerosis, a key driver of heart disease. By evaluating plaque buildup and arterial thickness, it identifies cardiovascular risks before major events occur. Since heart disease risk rises postmenopause, early vascular screening allows for timely preventive strategies.

Incorporating ultrasound into routine assessments enables early intervention, guiding lifestyle and medical management to reduce heart disease risks. Given that cardiovascular disease is the leading cause of death in women, proactive imaging supports a healthier transition into menopause.

Recommended Checkups:
• Lipid Panel: Monitors cholesterol and triglyceride levels.
• Blood Pressure Monitoring: High blood pressure is a silent risk factor for heart disease.
• Blood Glucose and Hemoglobin A1c: Helps detect diabetes or prediabetes, which increases heart risk.
• Electrocardiogram (ECG) or Stress Test: Assesses heart rhythm and function, especially for those with symptoms or risk factors.


2. BREAST AND REPRODUCTIVE HEALTH
The risk of breast cancer and other gynecological conditions increases with age, making routine screenings crucial.

Recommended Checkups: • Mammogram: Detects early signs of breast cancer. • Pap Smear and HPV Test: Screens for cervical cancer. • Pelvic Ultrasound: Assesses the uterus and ovaries for abnormalities.


3. OSTEOPOROSIS AND BONE HEALTH
Estrogen is crucial for bone density maintenance. Its decline accelerates bone loss, increasing the risk of osteoporosis and fractures, particularly in the hips, spine, and wrists.

Recommended Checkups: • Bone Density Scan (DEXA Scan): Measures bone mineral density and assesses fracture risk. • Vitamin D and Calcium Levels: Ensures adequate levels for bone strength. • Parathyroid Hormone (PTH) and Thyroid Function Tests: These help assess calcium metabolism and overall bone health.



STEP UP TO BONE HEALTH SCREENING

Proactive health screening is designed to detect potential health problems earlier, so you have more options and potentially better outcomes. That said, here are a few additions commonly recommend for women as they enter menopause. All of these can be done through your regular ObGyn or PCP, but it’s important to understand that they are looking for disease, not imbalances that can lead to disease.

• Bone Density Test
• Request a bone density scan if you have not had one by menopause or age 50.
• Blood Work
• Get comprehensive blood work that goes beyond the basic CBC and chemistry panel, including vitamin D, omega 3 and 6 fatty acids, ferritin; hsCRP, homocysteine, fractionated lipid panel, uric acid; TSH, Free T4, Free T3, Reverse T3; HbA1c.
• Pelvic Exam
• Even though routine pelvic exams are no longer recommended for asymptomatic women, changes related to menopause such as atrophy and lichen sclerosus, both of which can contribute to painful sex, as well as skin cancer can be detected early.



4. COGNITIVE DECLINE AND BRAIN HEALTH
Studies suggest that estrogen has neuroprotective properties, and its decline may contribute to an increased risk of cognitive decline and conditions like Alzheimer’s disease.

Recommended Checkups: • Cognitive Screening (e.g., MoCA or MMSE): Helps detect early signs of cognitive impairment. • Vitamin B12 and Folate Levels: Essential for brain function and mental clarity. Neurological Assessment: For those experiencing memory loss or cognitive difficulties.


5. METABOLIC SYNDROME AND WEIGHT GAIN
Menopausal women often experience weight gain due to hormonal changes and a slower metabolism. This increases the risk of metabolic syndrome, a cluster of conditions that heightens the risk for heart disease, stroke, and diabetes.

Recommended Checkups: • Body Mass Index (BMI) and Waist Circumference Measurement: Evaluates obesity-related risk factors. • Fasting Blood Sugar and Insulin Levels: Screens for insulin resistance and diabetes. • Liver Function Tests: Helps detect fatty liver disease, often linked with metabolic syndrome.


6. HORMONAL AND THYROID FUNCTION 
Hormonal imbalances, including thyroid dysfunction, are common in menopausal women and can mimic menopause symptoms such as fatigue, weight gain, and mood swings.

Recommended Checkups: • Thyroid Panel (TSH, Free T3, Free T4): Screens for thyroid dysfunction. • Sex Hormone Levels (Estrogen, Progesterone, and Testosterone): Helps assess hormonal imbalances.


Menopause brings significant changes that can impact long-term health, but proactive checkups and lifestyle modifications can help mitigate these risks. Women should work closely with their healthcare providers to create a personalized health monitoring plan. Early detection and preventive care are key to maintaining optimal health and well-being during and after menopause.

For more information about our MENOSCAN program, visit: www.BARDDIAGNOSTICS.com or contact our NYC office at: 212.355.7017






RECENT FINDINGS RELATING HASHIMOTO’S THYROIDITIS WITH ABNORMAL VASCULARITY

By: Robert L. Bard, MD

A woman in her 70s presented for routine follow-up of a previously identified left thyroid nodule, though there was no immediate clinical indication for concern. 

Slide 1: On ultrasound imaging, the left thyroid lobe revealed a complex nodule with features that appeared likely benign. Notably, there were no suspicious characteristics such as irregular margins, microcalcifications, or abnormal vascularity.

In the right lobe, we observed a small, simple cyst—anechoic and well-circumscribed, consistent with benign features. However, situated just beneath the cyst was a hypoechoic area lacking the echogenic brightness typically associated with cystic thyroid lesions. This darker region raised suspicion due to its decreased reflectivity, potentially indicating underlying fibrosis or chronic inflammatory changes rather than a simple fluid-filled structure.

To further characterize these findings, we evaluated vascular flow using Doppler imaging. The left lobe lesion demonstrated internal complex components but lacked hypervascularity or flow patterns consistent with malignancy. In contrast, the right lobe's suspicious area prompted us to perform elastography (strain imaging), which revealed a dark blue signal in the region. This finding suggests increased stiffness in the tissue, which is commonly associated with edema or inflammatory infiltration—features that are often seen in early or non-fibrosing Hashimoto’s thyroiditis. These findings warrant closer follow-up and possible serologic correlation for thyroid autoimmunity (e.g., TPO antibodies).

Slide Two (below): In a separate view, the carotid artery appears as a dark red structure lateral to the thyroid. Medial to the artery lies a well-defined, low-vascular lesion. Its stable appearance over time, combined with its imaging characteristics, supports a benign etiology—most likely an inflammatory pseudonodule or a reactive lymph node, both of which are common in autoimmune thyroiditis.

These slides help illustrate a key principle in ultrasound interpretation: the transmission of sound through different tissues. Fluid-filled cysts tend to have high acoustic transmission, resulting in enhanced posterior echoes or acoustic enhancement—appearing whiter behind the cyst due to increased signal. In contrast, solid lesions with dense fibrosis or malignant components attenuate sound waves, leading to darker posterior shadows. Therefore, areas with poor posterior enhancement (i.e., low acoustic transmission) are more likely to represent fibrotic tissue or malignancy.




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